What are the benefits of Placenta injection?
This injection drug is made by extracting various growth factors, cytokines, and other bioactive substances from the human placentas of healthy Japanese mothers.
Placenta regenerates tissues, promotes cellular DNA synthesis, and regulates the autonomic nervous system.
Various effects of placenta injections have been reported, ranging from cosmetic effects such as improvement of skin wrinkles and dry skin to improvement of liver disorders, menopausal disorders, sleep disorders, autonomic nervous system disorders, fatigue, and joint pain.
Who we recommend placenta therapy for
Placenta injections are recommended for patients with the following symptoms.
- Chronic fatigue, eye strain
- Shoulder stiffness, back pain, knee and other joint pain
- Muscle pain and muscle fatigue
- Dry skin and atopic dermatitis
- Cold sensitivity, menstrual irregularities, menstrual pain
- Menopausal disorders
- Skin dullness, rough skin
- Dysautonomia, anorexia, insomnia
- Liver dysfunction
- hay fever
※ Because the placenta stimulates sebum production, some patients develop temporary acne.
※ There are individual differences in effect.
Human placental extract
We have two type of human placenta injection drug, Laennec and Melsmon.
1 ampule / 2 mL
|Additives||・Pepsin (porcine origin)|
・Lactose (bovine origin)
How often should I inject placenta?
We recommend injections of 3 ampules twice a week for the first 4 weeks. After that, we recommend injections of 2 or 3 ampules once a week for maintenance.
|First 4 weeks||After 5 weeks|
|Placenta injection||Twice a week|
3 ampules per Injection
|Once a week|
2～3 ampules per Injection
Fees (tax included)
An initial consultation fee of 3,850 yen will be charged for those who are visiting our clinic for the first time. An appointment is required for the first visit.
No appointment is required for those who wish to receive only injections for the second and subsequent times. Please come to the clinic directly during office hours.
|Laennec・Melsmon (1 ampule＝2 mL)||Fees (Tax included)|
Safety and side effects of placenta injection
Japanese placenta drugs are very safe, but there are a few things we should let you know.
Safety against viruses and bacteria
The following contamination prevention measures are proceeded to prevent viral or bacterial contamination.
- Perform screening of material donors for viruses and other infectious diseases by a physician
- All the materials used for placenta products have passed acceptance tests for hepatitis B and C and AIDS (acquired immunodeficiency syndrome) viruses.
- Various virus inactivation processes which were scientifically proven are used in the manufacturing process.
- The final product is tested negative for viruses such as hepatitis B and C, AIDS, adult T-cell leukemia, and Fifth disease.
Since the launch of MELSMON in 1956 and LAENNEC in 1974 to the present, there has not been a single case of infection reported, including Creutzfeldt-Jakob disease.
However, since the risk of transmission of variant Creutzfeldt-Jakob disease, etc. cannot be completely ruled out theoretically, people who have received placenta injections are not allowed to donate blood afterward in Japan. Please do your own research on blood donation restrictions in your country.
Adverse reactions and side effects
- Internal bleeding, pain, rash, heat, itching, or induration at the injection site: If internal bleeding occurs, it will disappear spontaneously in 2 weeks, and others in 1-2 days. Repeated injections to the same site may cause the skin becoming thick and form induration (lumps). The lumps will improve with time, but may remain for a long time after repeated injections, and cannot be completely prevented. In our clinic, we change the injection site on the left and right each time to prevent this side effect.
- Allergic symptoms: Rash, urticaria, itching, and fever may occur. Although very rare, anaphylaxis (e.g., hypotension, dyspnea, convulsions, impaired consciousness, generalized erythema, mucous membrane disorders) has been reported.
- Liver dysfunction and headache (frequency unknown): Although extremely rare, if headache or hepatic dysfunction occurs, discontinue or change placenta injections.
- Other: Postmenopausal menstruation, minor menstrual irregularities and irregular genital bleeding, gynecomastia, drowsiness, lethargy, and weight gain have been reported. If you feel drowsy, do not drive a car, ride motorcycle, bicycle, or other vehicle.
Frequently asked questions about placenta injections
In addition to the above, we have compiled a list of questions about placenta injections that we often receive from patients.
Is placenta injection good for skin?
Placenta injections are ideal for people with skin problems that gradually progress with aging, such as dullness, lack of skin luster, sagging skin, and dry skin.
How long does it take to receive an injection?
The initial visit takes about 20 minutes because the doctor explains the procedure and the patient fills out a consent form.
After the second visit, the injection takes about 5 minutes.
How long do the effects of the injections last?
If you receive subcutaneous injections, the effect lasts about a week, so weekly injections are recommended.
The benefits to your skin and health obtained through a series of treatments will not disappear in a week.
Where do you give the injections?
The nurse will inject in your buttock or your arm.
The placenta is injected subcutaneously for slow absorption.
Which placenta injection do you recommend, Laennec or Melsmon?
Both have almost the same effect, but Laennec is recommended because it contains a larger amount of placenta.
If you experience side effects from Laennec, such as swelling or headaches, switch to Melsmon.
Since Melsmon contains benzyl alcohol, which has a pain-relieving effect, the injection is less painful.
Can return patients receive injections at any time?
Patients who receive an explanation about placenta injections from the doctor at their first visit and fill out a consent form do not need an appointment after the second visit.
You can receive placenta injections at any time by coming to the clinic during clinic hours. There is no consultation fee for just an injection.
Can I receive injections even though there has been an interval of more than one year?
Once you have had a consultation and written consent, you can receive injections at Hada no clinic anytime, no matter how many years have passed.
Many patients receive injections at our clinic only when they come to Japan.
Appointments and Enquiries
●HADA NO Clinic Koenji (TEL 03-5913-7435)
4F Anfini Building, 4-6-7 Koenji Minami, Suginami-ku, Tokyo
Mon.～Sat. : 10:30 am - 1:30 pm / 3:30 pm - 6:30 pm
Sun. and Public holiday : closed
●HADA NO Clinic Kojimachi (TEL 03-6261-7433)
B1 Chichibuya Building, 3-7-4 Kojimachi, Chiyoda-ku, Tokyo
Mon.～Fri. : 11:00 am - 2:00 pm / 4:00 pm - 7:00 pm
Sat. and Sun. : 10:00 am - 1:00 pm / 3:00 pm - 6:00 pm
Public holiday : closed
*Full appointments are required.
*We are very sorry, but our staff is not fluent in English. please speak slowly.
*Please note that 'telephone re-consultation fee' will be charged if a doctor responds to your medical questions.